Presented by: Dr. Serena Sanna, PhD, Director of Research at CNR, Italy

About the presentation: The gut microbiome, the collection of microorganisms, including bacteria, archaea, fungi, and viruses that live in our gastrointestinal track, associate with many aspects of human health. Among the many factors, early studies have shown that even host genetics correlate with gut microbiome variations. To robustly characterize these effects, we performed the largest genetic study of human gut microbiome from a single population and using metagenomic sequencing. Briefly we analyzed 207 taxa and 205 pathways representing microbial composition and function in 7,738 participants of the Dutch Microbiome Project. I will present the results identified also in the light of similar studies in other populations, discuss lessons learned, challenges and directions for future studies on gut microbiome aiming to understand interactions with the host genome.

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