Nadine Hempel, PhD, Associate Professor of Pharmacology at Penn State College of Medicine and Penn State Cancer Institute member, recently received the Agilent Seahorse XFp Grant Award for her work “Bioenergetics Analysis of Ovarian Cancer Patient Ascites.”
Hempel was one of two recipients of the award, sponsored by Agilent Technologies, and will receive an Agilent Seahorse XFp Analyzer, a tool that can quickly report the metabolic rates of cells for research purposes.
The goal of the Hempel lab is to understand the molecular mechanisms that regulate tumor cell metastasis. Movement of cancer cells from the primary tumor to distant metastatic sites represents the most lethal stage of cancer progression, due to difficulties in detection, isolation and effective targeted treatment of metastatic lesions. Hempel’s lab is specifically interested in elucidating the role of reactive oxygen species, antioxidant enzymes and mitochondrial function in regulating cellular signaling events that drive ovarian and bladder cancer metastasis.
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