PHS Biostatistics and Bioinformatics Seminar presented by Dr. Yukinori Okada, MD, PhD, Professor, Department of Genome Informatics, The University of Tokyo Statistical genetics is a research field that evaluates causality of human genetic variations on diseases, using statistical and bioinformatics approaches. Recent developments of sequencing technologies have provided human disease genome data of hundreds of […]

Presented by: Ben Lengerich, Postdoc and Alana Fellow, MIT Comp Sci and AI Lab & the Broad Institute In biomedical data analysis, an emerging trend focuses on contextualizing observations within biological and real-world processes. This approach facilitates high-resolution, context-specific insights by integrating information across datasets, moving beyond analyzing datasets in isolation. However, modern AI systems […]

Presented by: Shouhao Zhou, PhD, Assistant Professor, Division of Biostatistics and Bioinformatics; and Zizhong Tian, MS, PhD Candidate The accurate assessment of inter-rater agreement (IRA) for multiple-rater binary-response data is a pivotal task in psychological, social, and medical sciences. In this work, we introduce an advanced framework exploiting multivariate Bernoulli distribution to encapsulate the statistical […]